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Collagène : quels bienfaits pendant la grossesse et après ?

Collagen: what are the benefits during and after pregnancy?

Collagen is the most abundant and widespread protein in the human body; it provides elasticity, flexibility and resistance to tissues and organs, and also plays a major role at the mother-baby interface during pregnancy.
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Collagen is the most abundant and widespread protein in the human body. It provides elasticity, flexibility, and strength to tissues and organs, and also plays a major role in the mother-baby interface during pregnancy.
Did you know?

Le collagène est produit naturellement par le corps jusqu’à la vingtaine. Passé cet âge, sa production commence à chuter, les réserves sont alors vidées au fur et à mesure sans être remplacées…

What is collagen and what role does it play?

Collagen is the most abundant structural protein in the body. It accounts for a quarter of the body's proteins and is found in many tissues (skin, ligaments, muscles, bones, blood vessels, connective tissues, etc.). There are currently 29 known types of collagen, divided into different categories according to their structure and function. Among the most important are types I (skin, tendons, ligaments, bones, teeth, fibrocartilage), II and III. Type I collagen is the most abundant in the body. Type IV collagen is found in the uterus [1].

Collagen belongs to the family of structural proteins. It provides elasticity, flexibility, strength, hydration and healing properties to the body's structures. It is made up of three polypeptide chains wound into a helix, each composed of thousands of amino acids, elastin and glycoproteins. In the human body, it takes the form of a collagen network, often compared to "glue", responsible for the cohesion of tissues and organs — a kind of binding agent.

Why this product?

The collagen-enriched chocolate powder, for all (future) mamas.
As well as being indulgent, it contains collagen: an ally for hair and skin, designed to restore its elasticity and prevent and/or reduce stretch marks.

Our recommended product

Mamaload

Mamaload

Marine collagen powder, cocoa flavour

£20.69

£24.34
Pregnancy
Post-partum

Natural vitamin C for collagen formation

For skin and cartilage

3g of hydrolysed marine collagen type I

Collagen peptides 

Low molecular weight (2,000 Da)

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How does collagen change over time?

Le collagène est produit naturellement par le corps jusqu’à la vingtaine. Passé cet âge, sa production commence à chuter, le corps n’arrive plus à produire rapidement du collagène. Les réserves sont alors vidées au fur et à mesure sans être remplacées. A 35 ans, il ne reste plus que 80% de nos réserves de collagène [2].

Différents facteurs peuvent également accentuer la dégradation du collagène, notamment l’exposition au soleil, le tabac, la pollution ou encore certaines hormones.

Notre gamme de collagène grossesse aide à booster vos apports et compenser la chute de production : 

Essayez nos poudres enrichis en collagène. Team chocolat ? Testez Mamaload, au cacao cru et riche en collagène. Team café ? Déca Mama, goût café mais sans caféine, pour toutes les mamas. 

Tip

Un massage corporel et facial stimule le collagène naturellement. Il permet de bien hydrater la peau pouvant prévenir les vergetures.

How important is collagen during pregnancy?

Beyond its common structural roles in the body, collagen has other very specific roles during pregnancy. 

The cervix plays a crucial mechanical role during pregnancy: before term, it must remain closed and withstand the increasing mechanical load of the uterus as it accommodates the growing baby. At the time of birth, it must be supple enough to deform and dilate to allow the baby to pass through.[3]

To fulfil this mechanical role — both strong and flexible — the fibrous tissue of the cervix must be able to remodel, organise, and soften according to the stage of gestation. Collagen is found in the fibrous tissue of the cervix, particularly in the extracellular matrix, and it is thought that premature softening of this tissue during pregnancy may lead to preterm birth.[4]

Furthermore, abnormal collagen expression may be associated with certain pregnancy-related pathological conditions, such as recurrent miscarriage. Consequently, at the maternal-foetal interface, normal collagen expression may be essential to a successful pregnancy.

Collagen also plays an essential role in the uterus in relation to mother-foetus exchanges. During pregnancy, the embryo implants in the uterus and is surrounded by trophoblasts (the outer layer of cells that envelops the embryo, anchored to the uterine tissue and supplying nutrients). Collagen acts not only as a three-dimensional scaffold that binds cells and tissues together, but is also capable of regulating cell behaviour — which is the case for trophoblasts. It plays an essential role in improving the adhesion and development of trophoblasts at the mother-foetus interface [5].

During pregnancy, the body can undergo many changes, including the natural stretching of the skin — made up of collagen and elastin — around the abdomen to accommodate the growing baby.

Stretch marks can appear when the dermis does not have sufficient time to stretch following sudden weight gain around the abdomen. Once the skin has been stretched, it struggles to return to its normal state. Collagen supplementation during this period may therefore be a way to help prevent the appearance of stretch marks or to restore smooth, resilient skin.

La “relaxine” est une hormone libérée pendant la grossesse qui permet la relaxation musculaire autour de l’utérus au fur et à mesure que le bébé grandit et pendant l’accouchement. Cette hormone entraîne aussi des douleurs articulaires sur les autres parties du corps (genoux, hanches, coudes…). Les études ont montré que le collagène peut jouer un rôle dans la réduction des douleurs articulaires. On peut donc penser qu’une supplémentation en collagène peut aider à réduire ces douleurs articulaires pendant la grossesse et même durant les premiers jours de post-partum.[6]

En parallèle, la pratique d'une activité physique douce sera bénéfique. Pour en savoir plus, retrouvez notre article sur sport et grossesse.

La glycine est l’acide aminé le plus abondant dans le collagène, elle favorise un sommeil de qualité en agissant comme un neuromédiateur, apaisant et favorisant le sommeil.  

 Au cours du troisième trimestre de grossesse et durant les premiers mois de maternité, une supplémentation en collagène hydrolysé (2180 mg de glycine) pourrait être bénéfique pour la maman pour favoriser un sommeil réparateur [7]. Notre complément alimentaire sommeil apporte 3g de glycine.

 Pour en savoir plus, allez voir notre article sur glycine et grossesse.

Discover our products

Les suppléments de collagène sont les meilleurs compléments alimentaires grossesse pour soutenir le corps. 

Why does collagen matter after giving birth?

Collagen is very important after childbirth. It can help with many postpartum symptoms. 

How to stimulate collagen production?

It is important to consume foods rich in nutrients that help stimulate collagen production in your body.

En post accouchement il est assez commun de rencontrer des douleurs articulaires, notamment au niveau des genoux, coudes ou encore poignets. La supplémentation du dérivé de collagène peut être une alternative pour soulager ces douleurs articulaires et réparer le cartilage [8].

Différentes études montrent qu’une supplémentation quotidienne de collagène de type II non dénaturé permet d’améliorer l’extension de l’articulation du genou et de soulager les douleurs articulaires[9][10]. Le collagène hydrolysé (peptide de collagène), absorbé et distribué dans les tissus articulaires, possèderait des propriétés analgésiques et anti-inflammatoires [11].

Pour en savoir plus sur la nutrition pour se remettre de l'accouchement, retrouvez notre article alimentation post partum.

En post-partum, un phénomène existe et est appelé “effluvium télogène du post-partum” qui peut durer entre 2 à 6 mois où se produit une perte de cheveux abondante qui peut parfois faire peur. Elle est pourtant normale et transitoire.

Le collagène peut avoir un rôle sur vos cheveux, leur permettant de rester forts et nourris, ou encore sur vos ongles, leur évitant de se casser ou de se dédoubler.[12] Une consommation régulière de collagène hydrolysé a une influence positive sur la résistance et l’hydratation de la peau et des cheveux.

Pour plus de renseignements, vous pouvez aller lire notre article concernant la perte de cheveux en post partum.

Le collagène peut être consommé en parallèle de notre complément alimentaire chute de cheveux

For good healing after childbirth (whether by caesarean section or vaginal delivery, particularly in the case of tears), adequate levels of vitamin A, vitamin C, zinc, and good-quality protein are needed. Collagen may contribute to good post-birth healing, alongside a varied and balanced diet.

Furthermore, a study showed that medium and high doses of marine collagen administered after a caesarean section in rats can significantly promote healing of the uterine incision. Its promoting effect may be mainly linked to the mechanism of encouraging the formation of new capillaries in uterine scar tissue, as well as the growth and repair of collagen fibres and smooth muscle tissue. However, compared to the rat uterus, the human uterus has a different anatomical structure and physiological process. Therefore, further studies are needed to confirm with certainty a potential healing and restorative effect in women [13].

Post-partum challenge

Everything is ready for baby's arrival — but have you prepared things for YOU? Jolly Mama coaches you to help you better prepare for and navigate your post-partum

Collagen: what are the benefits during and after pregnancy?

Nos poudres Mamaload, Déca Mama, Collagène Mama sont riches en collagène. Nous utilisons du collagène de type I qui est le plus abondant dans le corps, il est notamment bénéfique pour les tissus et la peau. Nous avons également du collagène de type 3 qui fournit un réseau flexible pour le soutien cellulaire, le composant principal souvent trouvé dans la peau et qui est abondant pendant les premiers stades de la cicatrisation.

Notre complément alimentaire post partum est riche en vitamine C, zinc et vitamine E, qui aident à stimuler la production de collagène. Si vous allaitez, c'est un complément alimentaire compatible allaitement

Are collagen creams effective?

Collagen creams do exist. However, they are poorly absorbed and do not penetrate the skin barrier. This is because the collagen molecules they contain are too large to reach the deeper layers of the skin [14]. Creams and other cosmetic products therefore mainly have a moisturising and smoothing effect on the outer layer of the skin. They would also theoretically need to be applied several times a day, as their effect is very short-lived. 

A body and facial massage (for everyone's enjoyment) is a wonderful way to stimulate collagen naturally. These massages help keep your skin well moisturised, which can help prevent stretch marks. They also have different benefits depending on the area of the body massaged: on your legs, they stimulate blood circulation and can help prevent heavy legs; on your bust, they help tone the skin; on your tummy and hips, they help maintain smooth, supple skin!

Nourishing anti-stretch mark butter idea: mix shea butter, avocado oil, Inca Inchi vegetable oil and wheatgerm vegetable oil.

According to the results of these studies, taking collagen peptides improves skin hydration and elasticity and contributes to reducing facial wrinkles.[15]

What are the sources of collagen?

Les aliments riches en collagène

Les aliments naturellement riches en collagène sont : le porc, le bœuf, le poulet ou encore le poisson. 

Astuce : Si vous aimez le poulet et/ou le poisson, assurez-vous de consommer la peau qui est très riche en collagène.

Si vous voulez faire le plein de collagène, optez pour un bouillon de poulet ou de bœuf.

Le bouillon n’est pas à réserver uniquement au postpartum, mais peut-être un allié de choix durant la grossesse ou l’accouchement pour reprendre des forces. En plus il est très reminéralisant (riche en minéraux comme le fer, magnésium, zinc…) et faible en calories !

Notre gamme de bouillon d'os est déjà prête pour vous :  

Mama Poule, le bone broth à base d'os de poulet, contient 6g de collagène par portion.

Mama beef, à base d'os de boeuf, contient près de 15g de collagène par portion. 

Il n’existe pas de collagène végétal car il ne peut être produit que par les animaux. Le collagène “sans produit animal” n’existe pas. Seuls les produits animaux contiennent du collagène.

La vitamine C est un cofacteur important des enzymes impliquées dans la stabilisation de la triple hélice du collagène. Elle permet de stimuler la production de collagène.

Source : fruits notamment les agrumes, poivrons, brocolis et de nombreuses herbes aromatiques tel que le persil. 

Essential in collagen production.

Sources: beef/lamb, walnuts, spinach, mushrooms, lentils, wholegrains or cocoa.

An antioxidant, it neutralises the free radicals responsible for collagen breakdown.

Sources: spinach, nuts and seeds (walnuts, hazelnuts), avocados, dried apricots, and various oils (olive, rapeseed).

What about collagen food supplements?

On retrouve deux familles de collagène : le collagène marin (qui peut être extrait des poissons, algues, méduses, mollusques, etc) et le collagène de mammifères (porc, bovins).

Si vous vous demandez quel collagène choisir, voici nos conseils : 

Les compléments alimentaires sous forme de peptides de collagène (ou collagène hydrolysé) correspondent à des chaînes d’acides aminés plus courtes que celles qui composent le collagène dans notre corps. Ils partent ainsi plus vite dans la circulation sanguine pour être utilisés [16]. 

Le collagène va être ainsi directement absorbé par le corps, rendant donc ces compléments alimentaires plus efficaces.

Des études ont montré que des compléments alimentaires à base de collagène hydrolysé peuvent aider à prévenir l’apparition des vergetures et améliorer la fermeté de la peau [17]. 

Nos compléments alimentaires sous forme de poudre, comme Mamaload au cacao cru, contiennent du collagène sous forme de collagène marin hydrolysé. Notre snack Banana glow à la banane et pépites de chocolat est également enrichi en collagène !

Marine collagen or mammalian collagen?

Marine collagen or mammalian collagen? 

Marine collagen has advantages over mammalian collagen, as it can be easily extracted, is water-soluble and is safe because it is free from the risks of animal diseases and pathogens [18]. Indeed, outbreaks of bovine spongiform encephalopathy, transmissible spongiform encephalopathy and foot-and-mouth disease have heightened health concerns regarding the use of collagen and collagen-derived products from terrestrial animals in recent years [19].

Furthermore, fish collagen peptides have a superior antioxidant effect compared to porcine and bovine collagen peptides due to their relatively high content of glycine and proline (two amino acids) and their relatively high hydrophobicity, which facilitates increased lipid solubility [20].

Marine collagen peptides are biologically active, they have improved chemical and physical properties and enhanced function [21], as well as a number of bioactive properties such as antioxidant, anti-ageing of the skin, antimicrobial, antihypertensive and wound-healing activities [22].

Is there a risk associated with consuming collagen? 

The daily dose of collagen in the form of collagen peptides is 2.5 to 5 grams per day (i.e. 2,500 to 5,000 mg per day) for effects on the skin [23]. For an effect on joint relief, the daily dose of hydrolysed collagen is 10 grams per day and 40 mg per day for type II collagen [24].

Collagen is a source of non-essential amino acids, already produced by the human body.

The main precaution to take concerns daily doses (to avoid the risk of overdosing). 

For pregnant or breastfeeding women, this intake should be between 70 and 100 grams per day, from all sources combined.

In conclusion

As you will have gathered, collagen is one of the most abundant proteins in the human body, and supplementing with it — or with nutrients that may help stimulate its production — is well worth considering, especially during or after pregnancy. It is important for many general functions, such as helping to maintain skin elasticity and hydration, and during or after pregnancy it plays a particularly key role at the maternal-foetal interface, where its expression is essential. It can also help address some of the minor discomforts that come with pregnancy: stretch marks, joint pain, and hair loss.

Source 1 : Collagen Structure and Stability, 2009

Source 2 : An Overview of the Beneficial Effects of Hydrolysed Collagen as a Nutraceutical on Skin Properties, 2015

Source 3 : Collagen Fiber Orientation and Dispersion in the Upper Cervix of Non-Pregnant and Pregnant Women, 2016

Source 4 : Collagen at the Maternal-Fetal Interface in Human Pregnancy, 2020

Source 5 : Collagen Type IV at the Fetal–Maternal Interface, 2015

Source 6, 8 : Role of Collagen Derivatives in Osteoarthritis and Cartilage Repair: A Systematic Scoping Review, 2020

Source 7 : Multifarious Beneficial Effect of Nonessential Amino Acid, Glycine: A Review, 2017

Source 9 : Undenatured Type II Collagen (UC-II®) for Joint Support, 2013

Source 10 : Efficacy and Tolerability of an Undenatured Type II Collagen Supplement..., 2016

Source 11, 24 : Effectiveness of Collagen Peptide on Osteoarthritis, 2015

Source 12 : Oral Supplementation with Specific Bioactive Collagen Peptides Improves Nail Growth..., 2017

Source 13 : Marine fish peptides (collagen peptides) compound intake promotes wound healing..., 2020

Source 14 : Falten von innen glätten, 2015

Source 15 : The Effect of Oral Collagen Peptide Supplementation on Skin Moisture and the Dermal Collagen Network, 2015

Source 16 : Collagen vs Gelatin: Is One Better?, 2015

Source 17 : Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology, 2014

Source 18 : Biological Safety of Fish (Tilapia) Collagen, 2014

Source 19 : The Origin of Bovine Spongiform Encephalopathy: The Human Prion Disease Hypothesis, 2005

Source 20 : Progress of fish collagen as novel biomedical material, 2018

Source 21 : Fish Protein Hydrolysates: Production, Biochemical, and Functional Properties, 2000

Source 22 : Collagen from Marine Biological Sources and Medical Applications, 2018

Source 23 : Collagen Peptides and Cellulite Morphology, 2015

[1] Shoulders, Matthew D., et Ronald T. Raines. 2009. « Collagen Structure and Stability ». Annual Review of Biochemistry 78 (1): 929‑58. https://doi.org/10.1146/annurev.biochem.77.032207.120833.

[2] Sibilla, Sara, Martin Godfrey, Sarah Brewer, Anil Budh-Raja, et Licia Genovese. 2015. « An Overview of the Beneficial Effects of Hydrolysed Collagen as a Nutraceutical on Skin Properties: Scientific Background and Clinical Studies ». The Open Nutraceuticals Journal 8 (1). https://benthamopen.com/ABSTRACT/TONUTRAJ-8-29.

[3] Yao, Wang, Yu Gan, Kristin M. Myers, Joy Y. Vink, Ronald J. Wapner, et Christine P. Hendon. 2016. « Collagen Fiber Orientation and Dispersion in the Upper Cervix of Non-Pregnant and Pregnant Women ». PLOS ONE 11 (11): e0166709. https://doi.org/10.1371/journal.pone.0166709.

[4] Shi, Jia-Wei, Zhen-Zhen Lai, Hui-Li Yang, Shao-Liang Yang, Cheng-Jie Wang, Deng Ao, Lu-Yu Ruan, et al. 2020. « Collagen at the Maternal-Fetal Interface in Human Pregnancy ». International Journal of Biological Sciences 16 (12): 2220‑34. https://doi.org/10.7150/ijbs.45586.

[5] Oefner, C. M., A. Sharkey, L. Gardner, H. Critchley, M. Oyen, et A. Moffett. 2015. « Collagen Type IV at the Fetal–Maternal Interface ». Placenta 36 (1): 59‑68. https://doi.org/10.1016/j.placenta.2014.10.012.

[6] Honvo, Germain, Laetitia Lengelé, Alexia Charles, Jean-Yves Reginster, et Olivier Bruyère. 2020. « Role of Collagen Derivatives in Osteoarthritis and Cartilage Repair: A Systematic Scoping Review With Evidence Mapping ». Rheumatology and Therapy 7 (4): 703‑40. https://doi.org/10.1007/s40744-020-00240-5.

[7]  Razak, Meerza Abdul, Pathan Shajahan Begum, Buddolla Viswanath, et Senthilkumar Rajagopal. 2017. « Multifarious Beneficial Effect of Nonessential Amino Acid, Glycine: A Review ». Oxidative Medicine and Cellular Longevity 2017 (mars): e1716701. https://doi.org/10.1155/2017/1716701.

[8] Honvo, Germain, Laetitia Lengelé, Alexia Charles, Jean-Yves Reginster, et Olivier Bruyère. 2020. « Role of Collagen Derivatives in Osteoarthritis and Cartilage Repair: A Systematic Scoping Review With Evidence Mapping ». Rheumatology and Therapy 7 (4): 703‑40. https://doi.org/10.1007/s40744-020-00240-5.

[9] Lugo, James P., Zainulabedin M. Saiyed, Francis C. Lau, Jhanna Pamela L. Molina, Michael N. Pakdaman, Arya Nick Shamie, et Jay K. Udani. 2013. « Undenatured Type II Collagen (UC-II®) for Joint Support: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers ». Journal of the International Society of Sports Nutrition 10 (1): 48. https://doi.org/10.1186/1550-2783-10-48.

[10] Lugo, James P., Zainulabedin M. Saiyed, et Nancy E. Lane. 2016. « Efficacy and Tolerability of an Undenatured Type II Collagen Supplement in Modulating Knee Osteoarthritis Symptoms: A Multicenter Randomized, Double-Blind, Placebo-Controlled Study ». Nutrition Journal 15 (janvier): 14. https://doi.org/10.1186/s12937-016-0130-8.

[11] Kumar, Suresh, Fumihito Sugihara, Keiji Suzuki, Naoki Inoue, et Sriraam Venkateswarathirukumara. 2015. « A Double-Blind, Placebo-Controlled, Randomised, Clinical Study on the Effectiveness of Collagen Peptide on Osteoarthritis ». Journal of the Science of Food and Agriculture 95 (4): 702‑7. https://doi.org/10.1002/jsfa.6752.

[12] Hexsel, Doris, Vivian Zague, Michael Schunck, Carolina Siega, Fernanda O Camozzato, et Steffen Oesser. 2017. « Oral Supplementation with Specific Bioactive Collagen Peptides Improves Nail Growth and Reduces Symptoms of Brittle Nails ». Journal of Cosmetic Dermatology 16 (4): 520‑26. https://doi.org/10.1111/jocd.12393.

[13] Peng, Xue, Jinfeng Xu, Yuan Tian, Wenjun Liu, et Bing Peng. 2020. « Marine fish peptides (collagen peptides) compound intake promotes wound healing in rats after cesarean section ». Food & Nutrition Research 64 (août). https://doi.org/10.29219/fnr.v64.4247.

[14] « Falten von innen glätten ». 2015. DAZ.online. 7 mai 2015. https://www.deutsche-apotheker-zeitung.de/daz-az/2015/daz-19-2015/falten-von-innen-glaetten.

[15] Asserin, Jérome, Elian Lati, Toshiaki Shioya, et Janne Prawitt. 2015. « The Effect of Oral Collagen Peptide Supplementation on Skin Moisture and the Dermal Collagen Network: Evidence from an Ex Vivo Model and Randomized, Placebo-Controlled Clinical Trials ». Journal of Cosmetic Dermatology 14 (4): 291‑301. https://doi.org/10.1111/jocd.12174.

[16] « Collagen vs Gelatin: Is One Better? [How to Pick] ». HumanN (blog). Consulté le 15 avril 2022. https://www.humann.com/nutrition/collagen-vs-gelatin/.

[17] Proksch, E., D. Segger, J. Degwert, M. Schunck, V. Zague, et S. Oesser. 2014. « Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study ». Skin Pharmacology and Physiology 27 (1): 47‑55. https://doi.org/10.1159/000351376.

[18] Yamamoto, Kohei, Kazunari Igawa, Kouji Sugimoto, Yuu Yoshizawa, Kajiro Yanagiguchi, Takeshi Ikeda, Shizuka Yamada, et Yoshihiko Hayashi. 2014. « Biological Safety of Fish (Tilapia) Collagen ». BioMed Research International 2014. https://doi.org/10.1155/2014/630757.

[19] Colchester, Alan C. F., et Nancy T. H. Colchester. 2005. « The Origin of Bovine Spongiform Encephalopathy: The Human Prion Disease Hypothesis ». Lancet (London, England) 366 (9488): 856‑61. https://doi.org/10.1016/S0140-6736(05)67218-2.

[20] Chen, Hongchi, Xiaojuan Wei, Changqing Zhang, et Wei Zhang. 2018. « Progress of fish collagen as novel biomedical material ». Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi = Zhongguo Xiufu Chongjian Waike Zazhi = Chinese Journal of Reparative and Reconstructive Surgery 32 (9): 1227‑30. https://doi.org/10.7507/1002-1892.201802025.

[21] Kristinsson, H. G., et B. A. Rasco. 2000. « Fish Protein Hydrolysates: Production, Biochemical, and Functional Properties ». Critical Reviews in Food Science and Nutrition 40 (1): 43‑81. https://doi.org/10.1080/10408690091189266.

[22] Felician, Fatuma Felix, Chunlei Xia, Weiyan Qi, et Hanmei Xu. 2018. « Collagen from Marine Biological Sources and Medical Applications ». Chemistry & Biodiversity 15 (5): e1700557. https://doi.org/10.1002/cbdv.201700557.

[23] Schunck, Michael, Vivian Zague, Steffen Oesser, et Ehrhardt Proksch. 2015. « Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology ». Journal of Medicinal Food 18 (12): 1340‑48. https://doi.org/10.1089/jmf.2015.0022.

[24] Kumar, Suresh, Fumihito Sugihara, Keiji Suzuki, Naoki Inoue, et Sriraam Venkateswarathirukumara. 2015. « A Double-Blind, Placebo-Controlled, Randomised, Clinical Study on the Effectiveness of Collagen Peptide on Osteoarthritis ». Journal of the Science of Food and Agriculture 95 (4): 702‑7. https://doi.org/10.1002/jsfa.6752.

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