Fever is another defence mechanism, which helps to accelerate immune defences and slow down the multiplication of pathogens.
Acquired immunity
Unlike innate immunity, acquired immunity is specific to the pathogen that induced it in the past.
It is referred to as acquired immunity because it involves the recognition of the pathogen. The key players in acquired immunity are B and T lymphocytes.
Acquired immunity uses two types of immunity:
Cell-mediated
Cell-mediated immunity, or cellular immunity, uses T lymphocytes, which can directly destroy foreign particles. They are produced in the thymus.
Humoral
Humoral immunity, or antibody-mediated immunity, uses soluble molecules called antibodies (immunoglobulins), produced by B lymphocytes. When B lymphocytes encounter an infectious agent, they produce specific antibodies directed against it. These antibodies are proteins capable of binding to foreign proteins and destroying them. They are also known as immunoglobulins.
It is not possible, however, to discuss these two types of immune response entirely independently. Cells play a role in initiating antibody responses, with antibodies being the essential link in certain cell-mediated reactions.
There are memory T and B lymphocytes. These cells retain the memory of a pathogen. If that agent infects the body again, the response generated will be much faster. It is on this property of the immune system that vaccines are based.
Our body thus retains a memory of the bacteria and viruses it has previously encountered. An adult is estimated to hold memory of between 1 and 100 billion different antigens!