What are the consequences of magnesium deficiency?
An imbalance in magnesium levels in the body (hypomagnesaemia) can lead to undesirable neuromuscular, cardiac, or neurological disorders. Maintaining adequate magnesium levels in the body is therefore very important [13]. It is the key nutrient of a women's food supplement.
The vicious cycle of stress and magnesium
There is a link between magnesium deficiency and increased susceptibility to stress-related disorders. Moreover, stress itself can lead to magnesium depletion. This is known as the "vicious cycle of stress". To address this, studies show that increasing magnesium intake reduces stress, and that magnesium supplementation is beneficial in stressed individuals [14]. Magnesium may also help in cases of anxiety. [15]
Magnesium and hormonal balance
Magnesium plays a key role in hormonal balance, as it is essential for liver function and helps regulate our hormones: progesterone, oestrogen, and testosterone. It also regulates cortisol, the stress hormone. It is likewise important for the adrenal glands and blood sugar regulation/metabolism.
Some studies have shown that magnesium may significantly reduce the intensity and duration of premenstrual syndrome (mood changes, anxiety, depression, bloating, breast pain, water retention...). [16] [17] This is notably due to its effect on the hormonal imbalance. It can indeed broadly alleviate the symptoms of endometriosis [18], fibroids, and perimenopause in particular. Indeed, it is one of the menopause supplements recommended, in addition to a selection of menopause vitamins complementary.
Magnesium and hair
Stress is one of the factors that can cause or worsen hair loss. By acting on stress levels, magnesium may also have an effect on hair. Its antioxidant action also gives it a role in protecting the cells responsible for hair renewal.
Magnesium and metabolism
Magnesium contributes to lipid metabolism, protein synthesis, and the breakdown of glucose to release energy.
A lack of magnesium could contribute to the development of type 2 diabetes by increasing insulin resistance. A meta-analysis of 8 studies highlighted that magnesium supplementation could be a promising avenue for glycaemic control in diabetic patients [19].
Magnesium and bone health
At bone level, the crystals in a magnesium-deficient bone become larger, making the bone more fragile and susceptible to fractures. Furthermore, magnesium stimulates the proliferation of bone cells, which suggests that magnesium deficiency leads to a reduction in bone formation [20].
Other effects of magnesium deficiency
Magnesium contributes to the prevention of cardiovascular disease, diabetes, and osteoporosis [21].
It also has an anti-inflammatory effect [22].
It plays an important role in muscle activity: a magnesium deficiency can manifest as cramps and muscle spasms [23]. It may therefore help with leg cramps during pregnancy.
It also plays a role in combating headaches and dizziness.
Low magnesium levels are associated with a wide range of neurological conditions such as migraine, depression, and epilepsy. It plays a role in the mechanisms of learning and memory [24].
Low dietary magnesium intake has been associated with the risk of several types of cancer. Epidemiological studies have established a correlation between low magnesium intake and the risk of colon cancer [25].