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Le seed cycling : la solution pour réguler son cycle ?

Seed cycling: the solution for regulating your cycle?

Seed syncing, or seed synchronisation, is a naturopathic practice based on the various properties of seeds — in particular their potential benefits for hormonal imbalances.
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Take care mama

Vous venez d’arrêter la pilule ? Vous êtes en post partum ? Vous souhaitez tout simplement un cycle régulier ? Essayez le seed cycling, ce mélange de graine pensé pour réguler votre cycle. Au delà de ces actions sur le cycle, les graines ne contiennent que des bons nutriments pour votre santé globale.

The menstrual cycle

The menstrual cycle is divided into two phases, separated by ovulation:
 

The follicular phase

The follicular phase runs from day 1 of the cycle through to ovulation.

Under the action of follicle-stimulating hormone (FSH), oestrogen levels rise progressively from the first day of menstruation. Oestrogens support follicle maturation and endometrial growth. At the time of ovulation, oestrogen levels are at their peak, indicating that the follicle is mature. Luteinising hormone (LH) is then secreted. 
 

The luteal phase

The second phase of the cycle begins under the effect of LH and corresponds to the luteal phase. What remains in the follicle transforms into the corpus luteum, which secretes oestrogen and the hormone progesterone, which supports the implantation of the embryo in the endometrium of the uterus to initiate pregnancy.

If fertilisation does not occur, the corpus luteum degenerates, leading to a cessation of oestrogen and progesterone secretion. This hormonal drop triggers a new cycle with the onset of menstruation [1]. 

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How important is hormonal balance for the menstrual cycle?

Hormonal balance means the right hormones being secreted at the right time, in harmony. 
 

Our hormones, whether sexual or otherwise, all work in synergy. Just as in nature, if a species disappears or spring arrives too early it has consequences for the entire ecosystem, in our bodies if a hormone is secreted too much, too little, or at the wrong time, all the others are affected. 
 

So, when there is too much or too little oestrogen, this affects not only ovulation, endometrial quality and periods, but also the production of progesterone for example, of histamine (an inflammatory substance involved in gastric acid secretion, allergies, headaches, skin concerns…), bone health, brain health, muscle health, and liver function… 

Did you know?

Les graines de lin contiennent des lignanes, qui vont aider à équilibrer les niveaux d’oestrogènes dans l’organisme !

Excess oestrogen contributes to heavy periods, menstrual pain, breast pain [2], endometriosis, fibroids, premenstrual syndrome, and hormone-dependent cancers such as certain types of breast cancer [3]. 

Without sufficient oestrogen, the endometrium grows very little, and periods are consequently lighter and/or shorter. This can lead to fertility problems, as the quality and thickness of the endometrium are crucial factors in successful embryo implantation. Finally, given the impact of oestrogens on our mood, brain, libido, memory and sleep, a lack of oestrogen can also manifest through the following symptoms: memory loss, depression, anxiety, lethargy, night waking, reduced libido, vaginal dryness…

Insufficiently robust progesterone is problematic for fertility. In this case, the luteal phase (and therefore the time available for the embryo to implant in the endometrium) is shortened. Progesterone deficiency is also often at the root of miscarriages. Low progesterone production can also lead to the symptoms of premenstrual syndrome. 

Hence the importance of regulating our hormones — both for our gynaecological and reproductive health, and for our overall wellbeing!

A few tips

Les graines ne sont pas magiques, il est important à côté de cela d’avoir une alimentation adaptée (sans sucres raffinés, aliments transformés, inflammatoires, mais avec des bons gras et les nutriments nécessaires).

What is the principle behind seed cycling?

Le seed cycling, ou synchronisation des graines, est une pratique nutritionnelle qui a pour but d’aider et d’améliorer le cycle menstruel en recommandant la prise de quatres graines spécifiques.

Le seed cycling va permettre, en sélectionnant certaines graines, de rééquilibrer les taux d’hormones et ainsi d’éviter les désagréments liés au cycle menstruel en agissant sur les deux phases évoquées.
 

Le seed cycling permettrait d’aider dans le traitement du Syndrome Prémenstruel (SPM), souvent signe d’une fluctuation des taux circulants des hormones œstrogènes et progestérones. 

Il serait également indiqué dans le syndrome des ovaires polykystiques (SOPK), l'endométriose et l'infertilité, ainsi que pour atténuer des symptômes tels que les bouffées de chaleur, les sueurs nocturnes, la fatigue et les sautes d'humeur [4]. 

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Seed cycling during the follicular phase

Le seed cycling débute le premier jour des règles.

Pendant la phase folliculaire, les phytoestrogènes contenus dans les graines de lin peuvent contribuer à réguler les niveaux d’oestrogène. Le zinc contenu dans les graines de courge permet de favoriser la production de progestérone en préparation de la phase suivante du cycle.

Les graines de lin sont une des meilleures sources de lignanes, un type de phytoestrogènes. Les végétaux phyto œstrogènes sont 100 à 1000 fois moins forts que les œstrogènes, mais ils maintiennent un équilibre hormonal en ayant une action anti-oestrogénique ou oestrogénique si les niveaux sont respectivement trop hauts ou trop bas.

Ils se fixent de façon faible et temporaire sur les récepteurs des oestrogènes permettant à l’organisme d’éliminer les mauvais oestrogènes ou ils agissent directement sur l'hypophyse ou même sur d’autres glandes.

Ces lignanes augmentent ainsi la présence de la Sex Hormone Binding Globulin (SHBG), une protéine produite par le foie qui joue un rôle majeur dans le métabolisme et l'excrétion des œstrogènes. En favorisant le métabolisme des œstrogènes par le foie, les lignanes des graines de lin aident à réduire l'excès d'œstrogènes dans l'organisme [5].

Une étude a révélé que l'ingestion quotidienne de graines de lin pendant trois mois induirait une réduction significative du nombre de kystes ovariens, ainsi que de la taille des ovaires chez les femmes atteintes de SOPK. Cette même étude a également montré que la supplémentation en graines de lin a entraîné des menstruations régulières chez 33 % des femmes de la cohorte étudiée qui avaient auparavant des cycles irréguliers [6]. 

Flaxseeds are rich in magnesium (372 mg/100g), as are pumpkin seeds (535 mg/100g).

Magnesium plays a key role in hormonal balance, as it is essential for liver function and helps regulate our hormones: progesterone, oestrogen and testosterone. It also regulates cortisol, the stress hormone. It is equally important for the adrenal glands and the regulation of blood sugar levels/metabolism.

Most people do not consume enough magnesium-rich foods, and with stress, reserves are quickly depleted. Our bodies use up all their magnesium when we are stressed, not to mention that soil depletion makes it increasingly difficult to obtain through diet alone.

Some studies have shown that magnesium may lead to a significant reduction in the intensity and duration of premenstrual syndrome (mood changes, anxiety, depression, bloating, breast pain, water retention…). [7] 

Flaxseeds are also an excellent source of vitamin B1 (1.22 mg/100g), also known as thiamine, which contributes to a significant reduction in menstrual cramps, particularly in those suffering from dysmenorrhoea (pain occurring during menstruation) [8]. Research has indicated that women with a high dietary intake of thiamine present a notably lower risk of PMS. Thiamine is particularly effective at reducing depression and cramps associated with PMS [9].

Pumpkin seeds are an excellent source of zinc (7.5 mg/100g), a nutrient necessary for ovulation that helps stimulate follicles and the release of the LH hormone. It also plays a role in increasing progesterone levels as well as the production of FSH, which helps prepare the body for ovulation. 

Studies show that zinc supplementation has anti-inflammatory effects. By reducing inflammation and allowing better oxygen flow to the uterus, zinc can counteract the effects of prostaglandins and reduce both the incidence and duration of painful menstrual cramps. Research also shows that zinc reduces the severity of menstrual bleeding [10].

Furthermore, seeds contain a lot of fibre, which can help bind and eliminate toxins and hormones from the digestive tract, as well as regulate insulin. 

 The benefits of fibre are numerous:

They play a prebiotic role: fibres such as those from flaxseed (lignans) are often converted by gut bacteria into protective phyto-oestrogens.

Fibre is the food of the "good bacteria" in the gut microbiome. By consuming plenty of it — and in varied forms — we prevent the "good" bacteria from literally starving and the "bad" bacteria from taking their place, proliferating and disrupting several factors including hormonal regulation. Microbiome balance is also important in the detoxification of oestrogens, as they are excreted via stools. If the gut flora is imbalanced, certain bacteria could prevent the excretion of oestrogens, causing a surplus of them. Bad bacteria release an enzyme called beta-glucuronidase, which prevents the elimination of oestrogens via stools and causes them to recirculate in the blood, thereby contributing to an excess of oestrogens. 

They also act as a "broom" in the intestines, helping to move intestinal contents along and thereby regulate transit, facilitating the elimination of toxins and oestrogens.

Flaxseeds and pumpkin seeds contain high levels of fatty acids that help regulate FSH levels, reduce inflammation and support the production of sex hormones [11]. 

The conversion of linoleic acid from these seeds into other essential fatty acids contributes to the production of prostaglandins, which are essential for ovulation. A disruption in prostaglandin metabolism may be one cause of PMS symptoms [12]. Taking this seed blend may therefore help improve prostaglandin levels and thus have an effect on PMS and painful periods [13] [12].

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An ebook to better understand hormonal fluctuations and their impact on your wellbeing.
Learn to identify your phases, balance your cycle and rediscover energy and serenity in daily life.

Seed cycling: the solution for regulating your cycle?

Pour faire le plein de nutriments, vous pouvez cumuler cette pratique avec la prise d'un complément alimentaire pour tomber enceinte multivitamines par exemple.

Seed cycling during the luteal phase

It begins on the day of ovulation.

This second phase involves consuming sunflower and sesame seeds during the luteal phase to block excess oestrogen and stimulate progesterone production with the vitamin E found in sunflower seeds [14].

Sesame seeds are rich in lignans, and we have seen the many beneficial effects of these compounds. 

Zinc helps reduce inflammation during this phase and prepares the body for future menstruation. Sunflower seeds are a good source of zinc (4 mg/100g) and magnesium (325 mg/100g). Together with magnesium, it also acts to help prevent symptoms that appear before a period.

Sesame seeds also contain vitamin B6 (0.8 mg/100 g). This vitamin may act on symptoms such as anxiety, irritability, and premenstrual nervous tension [15].

High levels of oestrogen in the blood and low levels of progesterone have been observed in groups experiencing these symptoms. Vitamin B6 may reduce blood oestrogen, increase progesterone, and lead to an improvement in symptoms. 

The action of this vitamin goes even further. Indeed, it helps to lower levels of the hormone aldosterone. In excess, this hormone can cause symptoms such as water and salt retention, abdominal bloating, mastalgia, and weight gain. By reducing levels of this hormone, vitamin B6 may help to improve these symptoms [16].

Les graines de tournesol  contiennent de la vitamine E (33 mg/100g) qui va avoir une action non négligeable sur votre cycle. En effet, des études ont montré qu'elle améliore l'ovulation et la production de progestérone. Elle permettrait de réduire la sévérité dans les cas de dysménorrhée en diminuant la douleur associée aux menstruations [17]. 

Les graines sont également riches en acides gras et particulièrement en poly-insaturés comme les oméga 3. Une étude a montré que la co-supplémentation en oméga 3 et vitamine E a conduit à des améliorations significatives des scores liés à la dépression, l'anxiété et au stress.

Notre oméga 3 grossesse, Omega Mama, est tout à fait adapté pour toutes les femmes, enceintes ou non. Il permet de couvrir les besoins des femmes.

Sunflower seeds are rich in selenium, which supports the liver's detoxification of hormones [18].

Furthermore, in one study, patients with PCOS who received selenium supplements showed significantly reduced serum levels of dehydroepiandrosterone (DHEA, a pro-hormone involved in the synthesis of androgens and oestrogens [19]), and significantly reduced hirsutism [20].

These nutrients may also have an effect on hormones. Indeed, a supplementation study involving various nutrients including vitamin E and selenium showed that this intake led to a significant reduction in the LH/FSH ratio and testosterone levels in women with PCOS [21].

Pour faire le plein de nutriments, découvrez notre gamme de complément alimentaire femme, avec du magnésium, des oméga 3, du fer, etc. 

How to practise seed cycling in your daily life?

Commencez à pratiquer le seed cycling en vous basant sur votre cycle au premier jour de vos règles. 

Phase 1 (Graines de courge et graines de lin) : du premier jour des règles jusqu’à l’ovulation

Phase 2 (Graines de tournesol et graines de sésame) : de l’ovulation jusqu’à vos prochaine règles 

En théorie, l’ovulation se produit en milieu de cycle. Chez les personnes ayant un cycle de 28 jours, l’ovulation se produit en général au jour 14 (le premier jour du cycle correspond au premier jour des règles).

Cependant, de nombreuses femmes n’ont pas un cycle de 28 jours ou n’ont pas de cycles réguliers. En règle générale, chaque femme a tendance à avoir une phase lutéale qui dure sensiblement le même nombre de jours (en général 10 à 14 jours), et c’est la durée de la phase folliculaire qui a tendance à varier. Ainsi, en moyenne, l’ovulation a lieu 10 à 14 jours avant les règles.
 

Pour calculer son cycle, consultez notre article sur comment calculer son ovulation.

On ne se stresse pas sur les jours !

“Mais si ces graines ont un effet sur chaque étape du cycle, le corps a en réalité besoin de plus de temps pour se mettre à jour et c’est lui qui se charge de prendre ce dont il a besoin en fonction des besoins de chaque phase. Plutôt que de parler « cycling », il serait plus juste de parler de soutien nutritionnel. Manger des graines de sésame/lin en première partie de cycle ne provoquera bien sûr pas de déséquilibre hormonal et sera aussi bénéfique en deuxième partie de cycle car le corps les stocke pour les utiliser en fonction des besoins. " (Alix d’Antras, naturopathe)

Le seed cycling ne doit bien sûr pas remplacer une bonne hygiène de vie !

A healthy and varied diet.
Physical exercise.
Stress management.
And avoid environmental toxins and endocrine disruptors.

The effects of seed cycling may appear after several months. It can be helpful to keep notes in a journal to track the improvements observed!

You can consume a tablespoon of flaxseeds and pumpkin seeds for the first phase, and a tablespoon of sesame seeds and sunflower seeds for the second.

You can grind these seeds and add them to your drinks. This is a viable option — not too complicated if you have something to grind them with — but not very easy to store due to oxidation, and frankly not very tasty!

Le seed cycling peut aussi accompagner les femmes en périmenopause, lorsque le cycle devient irrégulier. Pour un soutien plus ciblé sur cette étape, vous pouvez explorer nos compléments ménopause.

Conclusion: the benefits of seed cycling

The benefits of seed cycling are unfortunately still not well studied. 
 

However, a number of studies have been conducted on the various seeds used in this practice. 
 

Furthermore, seeds have benefits beyond the menstrual cycle. For example, a mixture of flaxseeds and pumpkin seeds added to the diet may be useful in preventing complications of diabetes [22]. 

Thanks to their richness in micronutrients, the consumption of flaxseeds, sesame seeds and sunflower seeds has been associated with an improvement in risk factors for heart disease, such as high cholesterol and blood pressure. 

Furthermore, according to some studies, flaxseeds may offer protection against breast cancer, notably thanks to their lignin content [23] and also their omega-3 content [24]. 
 

That said, be patient — your body will need time to regulate itself and find its balance again!
 

Be careful not to self-supplement — food supplements are not without risk; they can interact with other supplements, foods and medications, and may not be suited to your personal situation, not to mention that choosing the right ones and adapting the dosages requires care. It is therefore preferable to seek advice from a healthcare practitioner specialising in nutrition (such as a naturopath or nutritional therapist).

Source 1 : Notions de Base du Cycle Menstruel – Tes Règles

Source 2 : Factors Effecting Mastalgia, 2016

Source 3 : Douleur mammaire - Problèmes de santé de la femme, Manuels MSD pour le grand public

Source 4 : What Is Seed Cycling? Effects on Hormones and Menopause, Healthline, 2019

Source 5 : Effect of Dietary Components, Including Lignans and Phytoestrogens, on Enterohepatic Circulation and Liver Metabolism of Estrogens and on Sex Hormone Binding Globulin (SHBG), 1987

Source 6 : Effects of Flax Seeds Supplementation in Polycystic Ovarian Syndrome, 2015

Source 7 : Magnesium supplementation alleviates premenstrual symptoms of fluid retention, 1998

Source 8 : What Is Seed Cycling? Effects on Hormones and Menopause, Healthline, 2019

Source 9 : The effects of vitamin B1 on ameliorating mental symptoms of premenstrual syndrome, Abdollahifard S, Maddahfar M, 2016

Source 10 : Zinc treatment prevents dysmenorrhea, 2007

Source 11 : Seed Cycling and Moon Syncing - What to Know about Syncing Your Hormones, Omne Wellness

Source 12 : Prostaglandins and premenstrual syndrome, 1992

Source 13 : Supplementation with omega-3 polyunsaturated fatty acids in the management of dysmenorrhea in adolescents, 1996

Source 14 : Does Seed Cycling Help Balance Hormones?, Reinagel, Nutrition Diva Monica, Scientific American

Source 15, 16 : Nutritional factors in the etiology of the premenstrual tension syndromes, Abraham GE, 1983

Source 17 : Comparison of the effect of vitamin E, vitamin D and ginger on the severity of primary dysmenorrhea, Pakniat H, et al., 2019

Source 18 : Can Seed Cycling Ease Menstrual Cycle Complications and Symptoms? – DUTCH Test

Source 19 : Mise au point sur la déhydroépiandrostérone (DHEA), Netgen, Revue Médicale Suisse

Source 20 : Selenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome, Razavi M, et al., 2016

Source 21 : The impact of a standardized micronutrient supplementation on PCOS-typical parameters, Hager M, et al., 2019

Source 22 : Antidiabetic Effect of Flax and Pumpkin Seed Mixture Powder, Makni M, et al., 2011

Source 23 : Dietary Flaxseed Inhibits Human Breast Cancer Growth and Metastasis, 2002

Source 24 : The Effect of Flaxseed in Breast Cancer: A Literature Review, Calado A, et al., 2018

[1] « Notions de Base du Cycle Menstruel – Tes Règles ». s. d.. https://www.yourperiod.ca/fr/normal-periods/menstrual-cycle-basics/#cycleComprehensive.

[2] Eren T, Aslan A, Ozemir IA, Baysal H, Sagiroglu J, Ekinci O, Alimoglu O. Factors Effecting Mastalgia. Breast Care (Basel). 2016 Jun;11(3):188-93. doi: 10.1159/000444359. Epub 2016 Mar 29. PMID: 27493619; PMCID: PMC4960349.        10.1159/000444359    

[3] « Douleur mammaire - Problèmes de santé de la femme ». s. d. Manuels MSD pour le grand public. Consulté le 13 avril 2021.
https://www.merckmanuals.com/fr-ca/accueil/probl%C3%A8mes-de-sant%C3%A9-de-la-femme/maladies-du-sein/douleur-mammai  e.

[4]  « What Is Seed Cycling? Effects on Hormones and Menopause ». 2019. Healthline. 18 juillet 2019.
https://www.healthline.com/nutrition/seed-cycling.

[5] Adlercreutz H, Hockerstedt K, Bannwart C, et al. Effect of Dietary Components, Including Lignans and Phytoestrogens, on Enterohepatic Circulation and Liver Metabolism of Estrogens and on Sex Hormone Binding Globulin (SHBG). Journal of Steroid Biochemistry. 1987; 27 (4–6): 1135–1144. doi: 10.1016/0022-4731 (87)90200-7.        10.1016/0022-4731(87)90200-7    

[6] Fatima Farzana K, et al. Effects of Flax Seeds Supplementation in Polycystic Ovarian Syndrome. International Journal of Pharmaceutical Sciences Review and Research. 2015;31(1), 113–119.

[7] Walker AF, Souza MCD, Vickers MF, Abeyasekera S, Collins ML, and Trinca LA. Magnesium supplementation alleviaes premenstrual symptoms of fluid retention. Journal of Women's Health. 1998;7(9):1157-1165. doi: 10.1089/jwh.1998.7.1157.        10.1089/jwh.1998.7.1157    

[8]  « What Is Seed Cycling? Effects on Hormones and Menopause ». 2019. Healthline. 18 juillet 2019. https://www.healthline.com/nutrition/seed-cycling.

[9] Abdollahifard S, Maddahfar M. The effects of vitamin B1 on ameliorating of mental symptoms of the premenstrual syndrome. European Psychiatry. 2016;33:s335. doi:10.1016/j.eurpsy.2016.01.745.        10.5539/gjhs.v6n6p144    

[10] Eby GA. Zinc treatment prevents dysmenorrhea. Medical hypotheses. 2007;69(2):297-301. doi: 10.1016/j.mehy.2006.12.009.        10.1016/j.mehy.2006.12.009    

[11] « Seed Cycling and Moon Syncing - What to Know about Syncing Your Hormones ». s. d. Omne Wellness. https://www.omnewellness.com/blog/menstrualcycle.

[12]  Koshikawa N, Tatsunuma T, Furuya K, Seki K. Prostaglandins and premenstrual syndrome. Prostaglandins Leukot Essent Fatty Acids. 1992 Jan;45(1):33-6. doi: 10.1016/0952-3278(92)90099-5. PMID: 1546064.        10.1016/0952-3278(92)90099-5    

[13] Harel, Z., et al., Supplementation with omega-3 polyunsaturated fatty acids in the management of dysmenorrhea in adolescents. Am J Obstet Gynecol, 1996. 174(4): p. 1335-8.        10.1016/s0002-9378(96)70681-6    

[14] Reinagel, Nutrition Diva Monica. s. d. « Does Seed Cycling Help Balance Hormones? » Scientific American. https://www.scientificamerican.com/article/does-seed-cycling-help-balance-hormones/.

[15] Abraham GE. Nutritional factors in the etiology of the premenstrual tension syndromes. J Reprod Med. 1983 Jul;28(7):446-64. PMID: 6684167.

[16]  Abraham GE. Nutritional factors in the etiology of the premenstrual tension syndromes. J Reprod Med. 1983 Jul;28(7):446-64. PMID: 6684167.

[17]  Pakniat, Hamideh, Venus Chegini, Fatemeh Ranjkesh, et Mohammad Ali Hosseini. 2019. « Comparison of the effect of vitamin E, vitamin D and ginger on the severity of primary dysmenorrhea: a single-blind clinical trial ». Obstetrics & Gynecology Science 62 (6): 462‑68. https://doi.org/10.5468/ogs.2019.62.6.462

[18] « Can Seed Cycling Ease Menstrual Cycle Complications and Symptoms? – DUTCH Test ». s. d. https://dutchtest.com/2020/07/20/seed-cycling/.

[19]  Netgen. s. d. « Mise au point sur la déhydroépiandrostérone (DHEA) ». Revue Médicale Suisse. https://www.revmed.ch/RMS/2005/RMS-6/30132.

[20] Razavi, M., M. Jamilian, Z. Fakhrieh Kashan, Z. Heidar, M. Mohseni, Y. Ghandi, T. Bagherian, et Z. Asemi. 2016. « Selenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome ». Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme 48 (3): 185‑90. https://doi.org/10.1055/s-0035-1559604.

[21] Hager, Marlene, Kazem Nouri, Martin Imhof, Christian Egarter, et Johannes Ott. 2019. « The impact of a standardized micronutrient supplementation on PCOS-typical parameters: a randomized controlled trial ». Archives of Gynecology and Obstetrics 300 (2): 455‑60. https://doi.org/10.1007/s00404-019-05194-w.

[22] Makni, Mohamed, Hamadi Fetoui, Nabil K. Gargouri, El Mouldi Garoui, et Najiba Zeghal. 2011. « Antidiabetic Effect of Flax and Pumpkin Seed Mixture Powder: Effect on Hyperlipidemia and Antioxidant Status in Alloxan Diabetic Rats ». Journal of Diabetes and Its Complications 25 (5): 339‑45. https://doi.org/10.1016/j.jdiacomp.2010.09.001.

[23] Chen J, Stavro PM, &Thompson LU. Dietary Flaxseed Inhibits Human Breast Cancer Growth and Metastasis and Downregulates Expression of Insulin-Like Growth Factor and Epidermal Growth Factor Receptor. Nutrition and Cancer. 2002;43(2): 187-192. doi: 10.1207/s15327914nc432_9.        10.1207/S15327914NC432_9    

[24] Calado, Ana, Pedro Miguel Neves, Teresa Santos, et Paula Ravasco. 2018. « The Effect of Flaxseed in Breast Cancer: A Literature Review ». Frontiers in Nutrition 5 (février). https://doi.org/10.3389/fnut.2018.00004.

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