We have chosen methylated folates for our pregnancy snack, which are directly active and therefore more easily absorbed by the body. The vitamin B9 in Vanifique comes from a spinach extract and contains 5-methyltetrahydrofolate (5-MTHF), a form that is already ready to be used by your body. By contrast, synthetic folic acid must undergo several conversion steps before becoming active, and approximately 60% of women may have difficulty metabolising it due to a genetic variation in the MTHFR gene.